The book attempts to provide a rational explanation of Hahnemann's concept of miasms in the light of modern pathological findings. Well known principles of physics, chemistry, biology, genetics etc. have been logically co-related with homoeopathic philosophy to aid in better understanding of the concepts. The objective of the author is to develop a scientific exactitude towards the interpretation of various symptoms for better case management and to bring homoeopathy at par with the modern system. That changes at the molecular and cellular level of the human being are absolutely crucial to the totality is a fact well recognized by Dr. Vijayakar, and this treatise is a very humble attempt to build upon a solid foundation of homoeopathy free of all assumptions and presumptions.